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Whichever you can find more ammo for.

45ACP. Hit center of mass, they are most unlikely to get up again, as a friend told me. 9mm...not as certain.

Against the pressure wave shattering windows and turning the ceiling into debris it's better than nothing. 9mm has cost (lol not anymore) and...

9mm has a slight edge in magazine capacity, but .45 does make more of an impression. Main thing to keep in mind is that shot placement matters...